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. 2019 Mar 22;10:526. doi: 10.3389/fimmu.2019.00526

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Copyright © 2019 Ubah, Steven, Porter and Barelle.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Preclinical toxicity assessment of Quad-X™ tested in C57BL/6 mice. (A) The effect of treatment on the mean body weight of experimental mice. The results shown are the means ± SEM (n = 10). Data was analyzed using an ANOVA multiple comparison test and Dunnett's post analysis (p-value > 0.1 in all group comparisons). (B) The effect of treatment on the mean organ to body weight ratio of experimental mice. Results shown are the means ± SEM (n = 10). Data was analyzed using the non-parametric Kruskal–Wallis multiple comparison tests with a Dunn's pair-wise test (p-value > 0.1 in all group comparisons vs. Vehicle treated group).