Table 2.
Differences and comparisons of bacteria in phyla and genera among children with asthma, rhinitis and healthy controls.
| Phylum/Genus | Controls (n = 26) |
Asthma (n = 35) |
Rhinitis (n = 28) |
Asthma vs. Controls |
Rhinitis vs. Controls |
|---|---|---|---|---|---|
| mean ± SD (%) | mean ± SD (%) | mean ± SD (%) | FDR P-value | FDR P-value | |
| Proteobacteria/Escherichia | 0.59 ± 0.50 | 1.98 ± 2.43 | 1.68 ± 4.22 | 0.002 | |
| Firmicutes/Eubacterium | 0.05 ± 0.04 | 0.13 ± 0.12 | 0.06 ± 0.07 | <0.001 | |
| Firmicutes/Roseburia | 5.71 ± 4.21 | 3.03 ± 3.22 | 3.74 ± 4.01 | 0.009 | |
| Firmicutes/Faecalibacterium | 11.17 ± 6.51 | 7.00 ± 6.33 | 9.79 ± 6.33 | 0.015 | |
| Firmicutes/Clostridium | 0.85 ± 0.64 | 1.22 ± 1.07 | 1.43 ± 1.63 | 0.029 | |
| Firmicutes/SMB53 | 3.72 ± 3.47 | 2.10 ± 1.27 | 2.68 ± 2.04 | 0.030 | |
| Firmicutes/Ruminococcus | 3.48 ± 1.94 | 2.44 ± 1.95 | 4.20 ± 3.04 | 0.045 | |
| Firmicutes/Phascolarctobacterium | 0.05 ± 0.06 | 0.10 ± 0.14 | 0.08 ± 0.10 | 0.048 | |
| Firmicutes/Dialister | 0.42 ± 0.53 | 0.12 ± 0.18 | 0.13 ± 0.14 | 0.009 | 0.013 |
| Firmicutes/Dorea | 2.07 ± 1.32 | 2.27 ± 1.70 | 1.44 ± 0.77 | 0.040 | |
| Actinobacteria/Adlercreutzia | 0.05 ± 0.06 | 0.07 ± 0.10 | 0.12 ± 0.14 | 0.027 |
Data shown are mean ± SD of relative abundance of bacteria. The percent of total numbers of sequences are shown for each split level. Only taxonomic classification with more than 100 sequences or 0.01% of total sequences, and statistically significant differences are shown. P-values are calculated by MetaStat method with FDR adjustment for multiple testing.