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. Author manuscript; available in PMC: 2019 Mar 29.
Published in final edited form as: Methods Mol Biol. 2018;1604:217–227. doi: 10.1007/978-1-4939-6981-4_16

Figure 4. Z-mediated suppression of the IFNβ promoter-driven luciferase reporter activity.

Figure 4.

LASV Z, but not PICV Z, inhibits RIG-iN-induced IFN-β activation in a luciferase (LUC)-based promoter assay. 293T cells were transfected with two different concentrations [100 ng (gray bars) and 1,000 ng black bars)] of either an empty vector (V) or Z plasmids (LASV or PICV) together with IFN-β–LUC, β-Gal, and RIG-iN plasmids. neg, negative control (no RIG-iN transfection).