Table 3. . Pathogen targets on the ePlex blood culture panels.
Gram-positive panel | Gram-negative panel | Fungal panel |
---|---|---|
Phylogenetic targets | ||
Bacillus cereus group | Acinetobacter baumannii | Candida albicans |
Bacillus subtilis group | Bacteroides fragilis | Candida auris |
Corynebacterium | Citrobacter | Candida dubliniensis |
Cutibacterium acnes | Cronobacter sakazakii | Candida famata |
Enterococcus | Enterobacter (non-cloacae complex) | Candida glabrata |
Enterococcus faecalis | Enterobacter cloacae complex | Candida guilliermondii |
Enterococcus faecium | Escherichia coli | Candida kefyr |
Lactobacillus | Fusobacterium nucleatum | Candida krusei |
Listeria | Fusobacterium necrophorum | Candida lusitaniae |
Listeria monocytogenes | Haemophilus influenzae | Candida parapsilosis |
Micrococcus | Klebsiella oxytoca | Candida tropicalis |
Staphylococcus | Klebsiella pneumoniae | Cryptococcus gattii |
Staphylococcus aureus | Morganella morganii | Cryptococcus neoformans |
Staphylococcus epidermidis | Neisseria meningitidis | Fusarium |
Staphylococcus lugdunensis | Proteus | Rhodotorula |
Streptococcus | Proteus mirabilis | |
Streptococcus agalactiae | Pseudomonas aeruginosa | |
Streptococcus anginosus group | Salmonella | |
Streptococcus pneumoniae | Serratia | – |
Streptococcus pyogenes | Serratia marcescens | |
Pan-Candida | Stenotrophomonas maltophilia | |
Pan-Gram negative | Pan-Gram positive | |
– | Pan-Candida | |
Drug resistance determiance targets | ||
vanA | CTX-M | |
vanB | KPC | |
mecA | OXA† | – |
mecC | IMP | |
– | VIN | |
NDM |
The genetic loci identified by the three ePlex blood-culture panels are summarized here, including markers of taxonomic identity and determinants of antimicrobial resistance.
†The Gram-negative panel specifically targets the OXA types 23 and 48, but not other OXA-class genes that may be intrinsically encoded by some Gram-negative species (although not necessarily conferring carbapenem resistance).