Table 4. Randomized Participant Stress Test and Coronary Computed Tomographic Angiography Findings Intent-to-Treat Population, Imaging Stress Test vs Exercise Tolerance Test.
| Characteristic, Stress Test Summary | No./Total No. (%) | ||
|---|---|---|---|
| Total (n = 5179) | Imaging Stress Test (n = 3909) | Exercise Tolerance Test (n = 1270) | |
| Core laboratory summary, baseline ischemia | |||
| Severe | 2799/5167 (54.2) | 1748/3901 (44.8) | 1051/1266 (83.0) |
| Moderate | 1701/5167 (32.9) | 1600/3901 (41.0) | 101/1266 (8.0) |
| Mild | 351/5167 (6.8) | 317/3901 (8.1) | 34/1266 (2.7) |
| None | 254/5167 (4.9) | 226/3901 (5.8) | 28/1266 (2.2) |
| Uninterpretable | 62/5167 (1.2) | 10/3901 (0.3) | 52/1266 (4.1) |
| CCTA findingsa | |||
| Any obstructive disease ≥50% stenosis by CCTA | 3832/3836 (99.9) | 2785/2786 (>99.9) | 1047/1050 (99.7) |
| Multivessel disease ≥50% stenosis by CCTA | 2679/3390 (79.0) | 1923/2441 (78.8) | 756/949 (79.7) |
| Vessels ≥50% stenosis by CCTA | |||
| 0 | 4/2986 (0.1) | 1/2147 (0.0) | 3/839 (0.4) |
| 1 | 697/2986 (23.3) | 508/2147 (23.7) | 189/839 (22.5) |
| 2 | 938/2986 (31.4) | 699/2147 (32.6) | 239/839 (28.5) |
| ≥3 | 1347/2986 (45.1) | 939/2147 (43.7) | 408/839 (48.6) |
| Specific native vessels with ≥50% stenosis by CCTA | |||
| Left main | 40/3845 (1.0) | 37/2794 (1.3) | 3/1051 (0.3) |
| Left anterior descending | 3190/3677 (86.8) | 2286/2659 (86.0) | 904/1018 (88.8) |
| Proximal LAD | 1749/3739 (46.8) | 1189/2711 (43.9) | 560/1028 (54.5) |
| Left circumflex | 2354/3495 (67.4) | 1690/2546 (66.4) | 664/949 (70.0) |
| Right coronary artery | 2311/3359 (68.8) | 1668/2417 (69.0) | 643/942 (68.3) |
Abbreviations: CCTA, coronary computed tomographic angiography; LAD, left anterior descending.
a
Includes study and nonstudy CCTAs.