Figure 1. Necrotizing Sweet Syndrome With Pyoderma Gangrenosum–like Features.

A patient in his 60s with myelodysplastic syndrome (A) developed an erythematous necrotizing plaque on his left malar cheek (B). Necrotizing soft tissue infection was initially suspected on the basis of his fever, shock, and multiorgan dysfunction. He received a diagnosis of hematologic malignant neoplasm–associated necrotizing Sweet syndrome with pyoderma gangrenosum–like features. His skin lesions had a complete clinical response to systemic corticosteroid therapy.