Table 3. Cox Proportional Hazards Regression Multivariate Analysisa.
| Factor | HR (95% CI) | |
|---|---|---|
| DFS | OS | |
| Age ≥70 y | 1.50 (0.92-2.45) | 1.80 (1.20-2.67) |
| Immunosuppressed | 0.89 (0.32-2.52) | 2.17 (1.12-4.17) |
| Periorbital primary | 2.48 (1.00-6.16) | 1.47 (0.62-3.52) |
| PNI-positive disease | 1.90 (1.12-3.19) | 1.32 (0.87-2.00) |
| N2 or greater disease | 2.16 (1.13-4.16) | 2.43 (1.42-4.17) |
| Postoperative radiation therapy | 0.67 (0.40-1.15) | 0.59 (0.38-0.90) |
Abbreviations: DFS, disease-free survival; HR, hazard ratio; OS, overall survival; PNI, perineural invasion.
a
Results were controlled for recurrent tumor, lymphovascular invasion, differentiation, and T stage. Reference groups were age younger than 70 years, other primary site, and N0 disease.