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. 2018 Dec 17;173(2):185–186. doi: 10.1001/jamapediatrics.2018.3811

Table. Demographic Characteristics; Frequency of Cannabis Use; Scores on Depression, Anxiety, and Cannabis Use Disorder Screens; and Associations With Experiencing Marijuana-Related Hallucinations or Paranoia.

Cannabis Use/Mental Health Variable Total, No. (%) (N = 146) Hallucinations in Past 12 mo, No. (%) OR (95% CI)a Paranoia or Anxiety in Past 12 mo, No. (%) OR (95% CI)a
Never (n = 106) Ever (n = 40) Never (n = 97) Ever (n = 49)
Cannabis use disorder
CUD diagnosis 40 (27.4) 21 (52.5) 19 (47.5) 3.76 (1.69-8.34) 19 (47.5) 21 (52.5) 3.15 (1.46-6.78)
No diagnosis 106 (72.6) 85 (80.2) 21 (19.8) 1 [Reference] 78 (73.6) 28 (26.4) 1 [Reference]
Frequency of past-year marijuana use
Monthly or more 70 (47.9) 42 (60.0) 28 (40.0) 3.81 (1.71-8.50) 37 (52.9) 33 (47.1) 3.30 (1.58-6.89)
Once or twice 76 (52.1) 64 (84.2) 12 (15.8) 1 [Reference] 60 (78.9) 16 (21.1) 1 [Reference]
Anxiety screen
Positive, score ≥3 on GAD 26 (17.8) 16 (61.5) 10 (38.5) 1.84 (0.74-4.57) 13 (50.0) 13 (50.0) 2.32 (0.96-5.58)
Negative, score <3 on GAD 120 (82.2) 90 (75.0) 30 (25.0) 1 [Reference] 84 (70.0) 36 (30.0) 1 [Reference]
Depression screen
Positive, score ≥3 on PHQ 35 (24.0) 23 (65.7) 12 (34.3) 1.51 (0.66-3.45) 15 (42.9) 20 (57.1) 3.75 (1.69-8.36)
Negative, score <3 on PHQ 111 (76.0) 83 (74.8) 28 (25.2) 1 [Reference] 82 (73.9) 29 (26.1) 1 [Reference]

Abbreviations: CUD, cannabis use disorder, determined by the modified World Mental Health Composite International Diagnostic Interview2; GAD, Generalized Anxiety Scale; OR, odds ratio; PHQ, Patient Health Questionnaire 2.

a

Odds ratio (95% CI) logistic regression adjusts for age (continuous), sex, and race/ethnicity.