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. 2018 Sep 27;137(1):21–27. doi: 10.1001/jamaophthalmol.2018.4461

Table 2. Multivariable Cox Proportional Hazards Model for Sustained Reduction of at Least 1 Topical Antihypertensive Agent Without Subsequent Laser Trabeculoplasty or Glaucoma Surgery, Among iStent/CEIOL Patients Receiving at Least 1 Agent at Baseline.

Characteristic Hazard Ratio (95% CI) P Value
Age at first surgery (per year increase) 1.00 (0.99-1.01) .99
Female (reference: male) 1.04 (0.86-1.25) .69
Glaucoma diagnosis (reference: POAG)
Narrow angle 0.95 (0.73-1.24) .72
Secondary glaucomas 0.92 (0.65-1.31) .65
Calendar year of surgery, per year increase 1.04 (0.94-1.16) .43
Bilateral iStent/CEIOL (reference: unilateral iStent/CEIOL) 1.97 (1.64-2.37) <.001
Baseline number of topical antihypertensive agents (reference: 1 agent)
2 Agents 1.23 (0.98-1.54) .07
≥3 Agents 1.71 (1.37-2.13) <.001

Abbreviations: CEIOL, cataract extraction with intraocular lens implantation; POAG, primary open-angle glaucoma.