Figure 2. Retinal Detachment in Coats Disease.

Fundus photograph (A) and optical coherence tomography (OCT) (B) from a 7-year-old boy. C and D, Light micrographs with hematoxylin-eosin stain from 2 enucleated biorepository eyes. A comparison of OCT and light micrographs demonstrates corresponding structures, including hyperreflective linear cholesterol crystals (yellow arrowheads), retinal pigment epithelium excrescence (green arrowheads), and small intraretinal and subretinal hyperreflective dots in areas without exudates (white arrowheads) that may correspond with macrophages (white arrowheads) on light micrographs. Other OCT findings include subretinal fluid (blue arrowhead), exudates (yellow arrowheads), inner retinal wrinkling (brown arrowheads), small preretinal hyperreflective OCT dots (orange arrowheads), and the epiretinal membrane (pink arrowhead) are observed. The horizontal white dotted line on the photograph corresponds to the OCT line scan.