Table 3. Secondary End Points.
| Variable | No. (%) | Mean Difference, % (95% CI)a | P Value | |
|---|---|---|---|---|
| Sellick Group (n = 1735) | Sham Group (n = 1736) | |||
| Mortality | 30 (2) | 27 (2) | −0.2 (−1.0 to 0.7) | .69 |
| Suspected pneumonia within 24 h | 15 (0.9) | 10 (0.6) | −0.3 (−0.8 to 0.3) | .31 |
| Aspiration pneumonia | 4 (0.2) | 4 (0.2) | 0 (−0.3 to 0.3) | >.99 |
| Severe pneumonia | 2 (0.1) | 2 (0.1) | 0 (−0.2 to 0.2) | >.99 |
| Length of hospital stay, median (IQR), d | 3 (1-9) | 4 (1-9) | 0.3 (−0.2 to 0.8) | .89 |
| Length of hospital stay >28 d | 91 (5) | 93 (5) | 0.1 (−1.4 to 1.6) | .89 |
| Admission into ICU | 181 (10) | 201 (12) | 1.1 (−0.9 to 3.2) | .28 |
| Length of ICU stay, median (IQR), d | 5 (2-11) | 5 (2-10) | −0.4 (−1.9 to 1.1) | .58 |
| Adverse eventsb | 276 (16) | 256 (15) | −1.2 (−3.6 to 1.2) | .34 |
| Serious adverse eventsc | 200 (12) | 211 (12) | 0.6 (−1.5 to 2.8) | .57 |
Abbreviations: ICU, intensive care unit; IQR, interquartile range.
a
Mean difference is calculated as Sellick group minus sham group.
b
Systematically included the following categorical end points: pulmonary aspiration, aspiration pneumonia, difficult and impossible tracheal intubation, traumatic complications, postoperative reintubation, admission into ICU, and mortality, which were present in 83% of patients with adverse events.
c
Systematically included the following categorical end points: severe aspiration pneumonia, impossible tracheal intubation, postoperative reintubation, admission into ICU, and mortality, which were present in 83% of patients with serious adverse events.