Table 3. Odds Ratio for the Primary Outcome Venous Thromboembolism/Death and Secondary Outcome Bleeding Eventa.
| Comparison | VTE/Death | Bleeding Event | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjustedb | Unadjusted | Adjustedb | |||||||
| OR (95% CI) | P Value | OR (95% CI) | P Value | P Value for Inferiority | OR (95% CI) | P Value | OR (95% CI) | P Value | P Value for Inferiority | |
| None vs anticoagulant only | 3.52 (2.40-5.15) | <.001 | 5.13 (3.74-7.02) | <.001 | NA | 1.33 (0.70-2.53) | .38 | 1.20 (0.72-2.00) | .49 | NA |
| Aspirin only vs anticoagulant only | 0.82 (0.66-1.02) | .07 | 0.85 (0.68-1.07) | .23 | .007 | 0.81 (0.64-1.02) | .08 | 0.80 (0.63-1.00) | .05 | <.001 |
| Both vs anticoagulant only | 1.04 (0.79-1.36) | .80 | 1.01 (0.77-1.32) | >.99 | NA | 1.25 (0.95-1.65) | .11 | 0.98 (0.75-1.28) | .90 | NA |
Abbreviations: NA, not applicable; OR, odds ratio; VTE, venous thromboembolism.
a
Confounders considered in propensity score model include age and age squared, body mass index and body mass index squared, preoperative hemoglobin, platelets and creatinine, sex, American Society of Anesthesiologists (ASA) status, race/ethnicity, smoking status, insurance, marital status, preoperative narcotic, steroid or antiplatelet use, bleeding disorder, history of deep vein thrombosis or pulmonary embolus, use of assistive devices, Elixhauser variables, surgical approach, operative duration, pneumatic compression devices, foot pumps, tranexamic acid, and anesthesia type.
b
Risk-adjusted model.