Table 1.

Summary of sera tested for reactivity with epsilon toxin or PA83 by Western blotting.

Test group	Total number of sera tested	Number of sera reactive with epsilon toxin	Number of sera reactive with PA83	Number of sera which did not react with PA83	Sera reactive with epsilon toxin but not with PA83
					n	%
CDMS	65	18	4	61	14	23
CDMS control	65	7	2	63	5	8
CIS	20	7	0	20	7	35
CIS control	20	2	0	20	2	10
ON	44	9	0	44	9	20
ON control	44	8	2	42	6	14
Total CDMS/CIS/ON	129	34	4	125	30	24
Total controls	129	17	4	125	13	10

CDMS: clinically definite multiple sclerosis; CIS: clinically isolated syndrome; ON: optic neuritis.