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. 2019 Mar 29;20:53. doi: 10.1186/s12881-019-0787-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Genogram of a multiply affected family with Progressive Pseudorheumatoid Dysplasia. Proband is denoted by the arrow. Full symbols designate affected individuals. Sequencing of the WISP3 gene revealed the affected individuals (V:1, III:13) to be homozygous for a novel c.257G > T mutation