Table 4.
The allele frequency comparison between the meta-analysis and 1000 Genomes Project
| Polymorphism | Populations | Meta-analysis (alleles frequencies) | 1000 genomes (alleles frequencies) | ||||
|---|---|---|---|---|---|---|---|
| Case | Control | ||||||
| C | T | C | T | C | T | ||
| rs2569190 (C-260T) | East Asian | 0.43 | 0.57 | 0.5 | 0.5 | 0.43(EAS) | 0.57(EAS) |
| European | 0.51 | 0.49 | 0.53 | 0.47 | 0.51(EUR) | 0.49(EUR) | |
| America | 0.53 | 0.47 | 0.53 | 0.47 | 0.47(AMR) | 0.53(AMR) | |
| All | 0.51 | 0.49 | 0.52 | 0.48 | 0.53 | 0.47 | |
| C-159T | East Asian | 0.44 | 0.56 | 0.47 | 0.53 | NA | NA |
| European | 0.53 | 0.47 | 0.52 | 0.48 | NA | NA | |
| Indian | 0.49 | 0.51 | 0.44 | 0.46 | NA | NA | |
| All | 0.49 | 0.51 | 0.5 | 0.5 | NA | NA | |
NA Not Available, EAS East Asian ancestry, EUR European ancestry, AMR Admixed American, All overall individuals from Phase 3 of the 1000 Genomes Project