Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 29;17:102. doi: 10.1186/s12967-019-1851-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 9 — PCDH17 expression is associated with distinct gene signatures in AML. a GSEA plots show enrichment of EZH2 and SNF5 gene sets in PCDH17 high expressers versus low expressers. b GSEA comparison of PCDH17 high expressers versus low expressers shows enrichment of genes down-regulated during early stages of ESC differentiation and genes up-regulated during late stages of ESC differentiation. c GSEA plots show up-regulation of AML HSC/LSC signature genes in PCDH17 low expressers versus high expressers. d GSEA plots show enrichment of FLT3-ITD and NPM1 gene sets in PCDH17 low expressers versus high expressers. e GSEA plot shows enrichment of EMT-related signature in PCDH17 high expressers versus low expressers. The normalized enrichment scores (NES) and P values are indicated in each plot. ESC, embryonic stem cell