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. 2019 Mar 29;38:139. doi: 10.1186/s13046-019-1134-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — NF chemical structure and the inhibitory mechanism of action in GBM. a Chemical and 3D structure of NF. b Schematic presentation of the mechanism underlying NF-induced inhibition of GBM and relevant molecular mechanism referring to the SOX2-AKT/STAT3-Slug signaling pathway