Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 29;39:12. doi: 10.1186/s40880-019-0356-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — The origins of biomarkers for liquid biopsy. Molecular alterations of circulating materials, such as cell-free DNA, circulating tumor cells, exosomes, and circulating nucleosomes and RNA, can be used as biomarkers for cancer diagnosis and prognosis. Genetic biomarkers can be identified via mutational profiling of nucleic acids extracted from circulating tumor cells. Epigenetic biomarkers can be obtained via methylation profiling and nucleosome foot printing of cell-free DNA, circulating tumor cells, and circulating nucleosomes and RNA