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. 2019 Mar 29;10:14. doi: 10.1186/s13293-019-0228-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Rate of change in MMSE score. Rate of change scatterplot and group trajectories in model-adjusted MMSE score over the study period for each of the eight sex/genotype/surgical exposure groups. Time “0” corresponds to study enrollment. Each point represents an individual visit. MMSE Mini-Mental State Examination