Table 3.

Rates of change in cognitive test scores in men vs. women

		Non-surgical men (slope)	Non-surgical women (slope)	Surgical men (slope)	Surgical women (slope)	Surgical exposure main effect (p value)	Sex effect—no surgical exposure (p value)	Sex effect—surgical exposure (p value)
Global cognitive function tests	MMSE	− 0.02528	− 0.01907	− 0.03539	− 0.02704	< 0.001	0.13	0.33
	CDR-SB	0.3568	0.2991	0.483	0.425	< 0.001	0.24	0.95
Memory-based tests	Logical Memory Delayed Recall	− 0.07798	− 0.08284	− 0.2623	− 0.2914	< 0.001	0.86	0.84
	CERAD Delayed Word List	−0.03858	− 0.0445	0.05887	− 0.05463	< 0.001	0.35	0.13
Attention-based tests	Digit Symbol	− 0.8686	− 0.948	− 1.244	− 1.271	< 0.001	0.31	0.65
	SDMT	− 1.312	− 0.8192	− 1.226	− 1.134	0.24	0.08	0.74
Executive function tests	Trails Making Test B	5.1	3.419	10.81	9.089	0.12	0.36	0.86
	Animal Category Fluency	− 0.4655	− 0.3809	− 0.5711	− 0.5551	< 0.001	0.15	0.35