. 2019 Mar 22;10:256. doi: 10.3389/fneur.2019.00256

Table 3.

Critical values of symptoms at which the performance becomes affected.

Significant variables	Area under the curve	Youden index	Clinical meaning of youden index
Reading
MMSE	0.69	28	MMSE < 28
Counting money
Tremor	0.33	2.33	Tremor > 1.5^a
MMSE	0.70	28	MMSE < 28
Eating soup
LID	0.42	4.33	LID > 7^a
Rigidity	0.35	2.5	Rigidity > 2.5
Taking medication
LID	0.68	3.25	LID < 4^a
Picking-up an object
Postural instability	0.22	4	Postural instability > 2
TUG
LID	0.62	37.94	LID < 3^a
Postural instability	0.22	4	Postural instability > 2
MMSE	0.74	28	MMSE < 28
TUG-GW
LID	0.71	18.27	LID < 2^a
Tremor	0.42	1.68	Tremor > 0.5^a
Postural instability	0.24	4	Postural instability > 2
TUG-O
Postural instability	0.26	4	Postural instability > 2
MMSE	0.71	28	MMSE < 28

Correspond to the sum of UDysRS or UPDRS scores of each limb assessed by a trained examiner.