Table 4.

Changes in biochemical parameters in the study groups

Biochemical parameters	Canthex™ (n=17)	Metformin (n=16)	P (between groups)
Fasting insulin
Baseline	29.515±28.895	27.106±19.463	0.782
EoT	26.896±27.694	19.995±20.918	0.427
P (within group)	0.538	0.123
Fasting blood sugar
Baseline	92.51±32.78	101.18±21.37	0.377
EoT	86.33±30.52	96.81±21.35	0.264
P (within group)	0.054	0.231
Total cholesterol
Baseline	173.76±39.41	161.31±31.80	0.327
EoT	174.05±36.15	158.37±32.67	0.201
P (within group)	0.977	0.642
Serum triglycerides
Baseline	152.33±73.87	140.31±69.42	0.633
EoT	143.81±51.35	155.68±86.88	0.633
P (within group)	0.316	0.340
Serum TSH
Baseline	4.90±5.85	3.29±2.52	0.316
EoT	2.85±2.77	2.13±1.03	0.340
P (within group)	0.062	0.137

P value between groups by unpaired Students’ t-test and within groups by paired Students’ t-test. EoT=End-of-treatment follow-up