Table 5.
Changes in obesity parameters in the study arms
| Obesity parameters | Canthex™ (n=17) | Metformin (n=16) | P (between groups) |
|---|---|---|---|
| Weight | |||
| Baseline | 66.35±9.02 | 67.93±17.93 | 0.748 |
| 4th week | 65.88±9.16 | 67.81±18.22 | 0.701 |
| 8th week | 65.58±10.25 | 66.62±17.96* | 0.838 |
| EoT | 64.88±10.68* | 65.81±18.04* | 0.857 |
| P (within group) | 0.029 | <0.001 | |
| BMI | |||
| Baseline | 26.73±3.59 | 25.77±5.10 | 0.537 |
| 4th week | 26.69±3.89 | 25.69±4.96 | 0.521 |
| 8th week | 26.43±4.13 | 25.24±4.94* | 0.457 |
| EoT | 26.13±4.19* | 24.93±4.98* | 0.459 |
| P (within group) | 0.036 | <0.001 | |
| Waist circumference | |||
| Baseline | 95.35±8.02 | 91.71±11.96 | 0.310 |
| 4th week | 94.67±9.02 | 91.18±12.01 | 0.350 |
| 8th week | 92.67±9.93* | 89.90±11.33* | 0.460 |
| EoT | 92.50±9.71* | 88.84±11.12* | 0.321 |
| P (within group) | <0.001 | <0.001 |
*Denotes significant reduction of that particular follow-up from baseline. P value between groups by unpaired Student’s t-test. P value within group by repeated-measures ANOVA followed by posthoc Tukey’s test. EoT: End of treatment, ANOVA: Analysis of variance