Table 7.

Effects of alfaxalone (25 μM) on evoked glutamatergic EPSCs.

Alfaxalone concentration	1st EPSC amplitude (pA)	1st EPSC 10%–90% rise-time (ms)	1st EPSC half-width (ms)	Paired pulse ratio (2nd/1st)	Baseline holding current (pA)
Control	−232 (−315.3 to −148.4)	5.5 (4–7)	10.1 (5.6–14.7)	1.71 (1.5–1.9)	−47.3 (−98.8 to 4.2)
25 μM	−215 (−317.8 to −113)	4.9 (3.8–6)	8.5 (2.6–14.5)	1.66 (1.52–1.8)	−40.06 (−83.9 to 3.8)
P =	0.43	0.1	0.35	0.31	0.38

Mean and 95% CI, n = 8 HMNs. Paired two tailed t-test.