Figure 2.

MMF preserves retinal function as measured by ERG. (A) ERG traces at the maximum light intensity (3.55 log cd s/m²), recorded 8 to 10 days after light exposure, showed that MMF rescued ERG responses in a dose-dependent manner from 50 to 100 mg/kg. (B) Treatment with 50 mg/kg MMF significantly increased b-wave, but not a-wave amplitudes following LIR. MMF at 65 and 75 mg/kg improved a- and b-wave amplitudes significantly, but the greatest effect was seen with 100 mg/kg MMF. Each dot represents the group average from the right and left eyes of each mouse (n ≥ 9 in each group). Mean ± SE of a- and b-wave amplitudes were plotted at different light intensities in each group. *P < 0.05.