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. 2019 Mar;60(4):1275–1285. doi: 10.1167/iovs.18-24398

Figure 5.

Figure 5

Retinal inflammation was reduced in MMF-treated animals. (A) At 24 hours after LIR, qPCR analysis of mRNA in the neural retina showed that the induction of proinflammatory genes Nlrp3 (3.6-fold), Casp1 (7.8-fold), Il-1β (14.1-fold), and TNF-α (9.5-fold) were suppressed in MMF-treated retinas. These experiments were replicated twice with n = 3. (B) Western blot analysis pNF-kB (ser536), total NF-kB, and Pro-Caspase1, from 1 to 24 hours after LIR. There were no significant changes in protein levels. Fold change was shown as mean ± SE, n = 3. *Fold change ≥ 2.