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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Hepatology. 2019 Mar 4;69(4):1520–1534. doi: 10.1002/hep.30346

Figure 4. Upregulation of AATF expression by TNF-α via SREBP1.

Figure 4.

(A and B) AATF protein expression in Hep2 and Huh7 cells upon TNF-α treatment. (C and D) AATF protein expression upon TNF-α treatment in the presence or absence of 25HC3S in HepG2 and Huh7 cells. (E and F) AATF protein expression in HepG2 and Huh7 cells transfected with control SiRNA or SREBP1 SiRNA with or without TNF-α treatment. Data are expressed as the mean ± SEM of three experiments (*p<0.05; **p<0.001).