Table 1. Demographic and clinical characteristics by nephritis status in 16 children and adolescents with systemic lupus erythematosus.
| Median (IQR) or n (%) | No Nephritis (n = 10) | Nephritis (n = 6) | p-value |
|---|---|---|---|
| Age (years) | 15.5 (11, 18) | 17 (15, 19) | 0.33 |
| Female | 9 (90%) | 6 (100%) | 0.42 |
| Race, n (%) | 0.23 | ||
| African-American | 5 (50%) | 6 (100%) | |
| Caucasian | 3 (30%) | 0 (0%) | |
| Asian | 1 (10%) | 0 (0%) | |
| Other | 1 (10%) | 0 (0%) | |
| eGFR*, ml/min/1.73m2 | 139.5 (130, 193) | 136.5 (102, 182) | 0.33 |
| Hepcidin, ng/ml | 27.9 (18.7, 59.7) | 71.5 (26.4, 116.4) | 0.19 |
| Hemoglobin, g/dl | 12.2 (11.7, 12.6) | 12 (11.2, 12.8) | 0.91 |
| Anemic**[18], n (%) | 3 (30%) | 3 (50%) | 0.42 |
| On anti-hypertensive medication | 0 (0%) | 5 (83.3%) | <0.001 |
| Systolic blood pressure, mmHg | 106 (104, 116) | 122 (118, 128) | 0.14 |
| Diastolic blood pressure, mmHg | 58 (58,68) | 65 (60, 68) | 0.31 |
| Pulse wave velocity, m/s | 3 (3.75, 4.55) | 4.4 (4.4, 4.9) | 0.10 |
*Estimated glomerular filtration rate;
**Defined as hemoglobin less than the 5th %ile for age and sex