Fig 1. Predicting value of CD4⁺ and CD8⁺CD45RC subsets for cancer and death.

(A), ROC curve analysis of CD4⁺CD45RC^high (blue line) and CD8⁺CD45RC^high (red line) T cells for cancer prediction. (B), Frequency of patients with a positive test for CD4⁺CD45RC^high as determined by ROC analysis (threshold 51.9%) according to presence or absence of cancer. (C&D), Survival free of cancer according to proportion of (C) CD4⁺CD45RC^high and (D) CD8+CD45RC^high T cells. Threshold values were determined according to ROC curve analysis.