Table 3.
List of accuracy, sensitivity, specificity, and ROC area of various bioinformatics tools used for predicting function of Hconf proteins from Shigella flexneri obtained after ROC analysis
| No. | Software name | Accuracy of prediction (%) | Sensitivity (%) | Specificity (%) | ROC area |
|---|---|---|---|---|---|
| 1 | BLAST | 100 | 100 | n/a | n/a |
| 2 | Pfam | 100 | 100 | 100 | 1 |
| 3 | HmmScan | 100 | 100 | 100 | 1 |
| 4 | SMART | 100 | 100 | 100 | 1 |
| 5 | Scanprosite | 72 | 100 | 12.50 | 0.662 |
| 6 | MOTIF | 100 | 100 | 100 | 1 |
| 7 | Interproscan | 100 | 100 | 100 | 1 |
| 8 | CATH | 80 | 100 | 16.70 | 0.539 |
| 9 | SUPERFAMILY | 84 | 100 | 20 | 0.54 |
| 10 | ProtoNet | 100 | 100 | 100 | 1 |
| 11 | Average | 93.6 | 100 | 64.35 | 0.774 |
ROC, receiver operating characteristic.