Table 1.

Oncogenic lncRNAs in non-small cell lung cancers

lncRNA	Mechanism of tumorigenesis	Biological activity	Reference PMID
PVT1	Decrease of miR-195	Cell proliferation and anti-apoptosis	[28848163]
	Decrease of miR-497	Cell growth, invasion, and anti-apoptosis	[29133127]
	Activation of MMP9 via sponging miR-200a and miR-200b	Cell invasion	[28731781]
LINC00152	Activation of EGFR/PI3K/Akt signaling pathway	Cell proliferation	[28787699]
	Activation of fibronectin and vimentin and decrease of p21	Cell invasion and anti-apoptosis
	Decrease of IL24 via interaction with EZH2	Cell proliferation, cell cycle, and anti-apoptosis	[28109288]
HOTAIR	Decrease of miR-613	Cell proliferation and invasion	[29187267]
H19	Activation of STAT3 via sponging miR-17	Cell growth, migration, and invasion	[29693721]
UPAT	Decrease of RASSF1 and CDH13 via increasing UHRF1	Cell proliferation	[30008828]
HOXD-AS1	Activation of MMP9 via sponging miR-133b	Cell migration and invasion	[29958139]
LINC00339	Activation of FOXM1 via sponging miR-145	Cell proliferation, invasion, and anti-apoptosis	[29906749]
MIAT	Activation of MMP9 via interaction with MLL	Cell proliferation, cell cycle, migration, and invasion	[29228680]

lncRNA, long non-coding RNAs.