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. 2018 Dec 28;16(4):e18. doi: 10.5808/GI.2018.16.4.e18

Table 3.

Oncogenic lncRNAs in glioblastomas

lncRNA Mechanism of tumorigenesis Biological activity Reference PMID
NEAT1 Activation of c-Met via sponging miR-449b-5p Cell proliferation, invasion, and migration [26242266]
Activation of SOX2 via sponging miR-132 Cell invasion and migration [30053878]

DANCR Activation of AXL via sponging miR-33a-5p, miR-33b-5p, miR-1-3p, miR-206, and miR-613, leading to activation of PI3K/Akt/NF-κB signaling pathway Anti-apoptosis and chemoresistance [29572052]
Activation of Wnt/β-cateninsignaling pathway Cell proliferation, and migration [29602127]

lncHERG Decrease of miR-940 Cell proliferation, invasion, and migration [29296221]

LINC00958 Activation of CDK2 via sponging miR-203 Cell proliferation and invasion [29570358]

SNHG7 Decrease of miR-5095 Cell proliferation, invasion, migration, and anti-apoptosis [29360452]

MCM3AP-AS1 Activation of KLF5 via sponging miR-211, leading to activation of AGGF1 Angiogenesis [29375300]

MNX1-AS1 Decrease of miR-4443 Cell proliferation, invasion, and migration [29678219]

LINC01446 Activation of TPT1 via sponging miR-489-3p Cell proliferation and invasion [30029885]

lncRNA, long non-coding RNAs.