Table 2.
Depression History Among Study Patients
| Depression History Variable | Patients, No. (%)a | P Value | ||
|---|---|---|---|---|
| All patients (n = 387) |
Case Patients (n = 129) |
Controls (n = 258) |
||
| Recorded diagnosis of depression | 33 (8.55) | 12 (9.4) | 21 (8.14) | .70 |
| Abnormal preoperative moodb | 19 (6.4) | 13 (13.0) | 6 (3.1) | .005 |
| “Depressed” preoperative mood | 7 (2.3) | 6 (6.0) | 1 (0.5) | .03 |
| Preoperative ICD-9 code for depression | 15 (3.9) | 5 (3.9) | 10 (3.9) | >.99 |
| Taking antidepressantc | ||||
| At time of surgery | 45 (11.7) | 21 (16.3) | 24 (9.4) | .05 |
| Within 1 y of surgery | 49 (12.7) | 23 (17.8) | 26 (10.2) | .03 |
| Depression historyd | 57 (14.7) | 28 (21.7) | 29 (11.2) | .01 |
Abbreviation: ICD-9, International Classification of Diseases, Ninth Revision.
aSome data were missing; 90 patients lacked documentation of their mood on the preoperative review of systems, 3 lacked documentation of a home medication list at time of surgery, and 280 patients did not have an additional medication list from within 1 year before surgery.
bMood recorded as anything other than “normal” on the preoperative review of systems.
cEither a first-line antidepressant (bupropion, selective serotonin reuptake inhibitor, or serotonin-norepinephrine reuptake inhibitor) or >1 antidepressant.
dDepression history was defined as having a recorded diagnosis of depression in the medical record, a depressed mood on preoperative review of systems, a preoperative ICD-9 code for depression, or a history of antidepressant use at the time of surgery or in the year before surgery.