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. 2019 Mar 29;2019(3):CD012212. doi: 10.1002/14651858.CD012212.pub2

1. Crystalloid volumes used in included studies.

Study Timing Comparator group Intervention group(s)
Ali 2003 Preoperative RL 2 mL/kg RL 15 mL/kg
Amireh 2009 Preoperative No crystalloid bolus RL 10 mL/kg
Ashok 2017 Intraoperative RL 10 mL/kg RL 30 mL/kg
Behdad 2011 Intraoperative RL 4 mL/kg RL 10 mL/kg
  Intraoperative   RL 20 mL/kg
Bennett 1999 Preoperative NS 1 to 2 mL/kg NS 15 mL/kg
Bhukal 2012 Intraoperative NS 4 mL/kg NS 10 mL/kg
Chaudhary 2008 Preoperative RL 2 mL/kg RL 12 mL/kg
Chauhan 2013 Preoperative RL 10 mL/kg RL 30 mL/kg
Chohedri 2006 Preoperative NS 2 mL/kg NS 20 mL/kg
Cook 1990 Preoperative No crystalloid bolus RL 20 mL/kg
  Preoperative   RL 20 mL/kg with 1 g/kg dextrose
Dagher 2009 Preoperative RL 10 mL/kg RL 30 mL/kg
Egeli 2004 Postoperative No crystalloid bolus D5RL 60 to 120 mL/hour
Elgueta 2013 Intraoperative RL 10 mL/kg/hour RL 30 mL/kg/hour
Elhakim 1998 Intraoperative No crystalloid bolus RL 1000 mL
Goodarzi 2006 Intraoperative RL 10 mL/kg/hour RL 30 mL/kg/hour
Gwak 2007 Intraoperative RL 6 mL/kg/hour RL 18 mL/kg/hour
Hashish 2007 Preoperative RL 10 mL/kg RL 30 mL/kg
Heidari 2012 Preoperative No crystalloid bolus RL 10 mL/kg
Heshmati 2004 Intraoperative No crystalloid bolus RL 4 mL/kg/hour
Holte 2004 Preoperative RL 15 mL/kg RL 40 mL/kg
Ismail 2017 Intraoperative RL 10 mL/kg RL 30 mL/kg
Keane 1986 Mixed No crystalloid bolus Intraoperative RL 1000 mL then postoperative 1000 mL D5W
Lambert 2009 Preoperative No crystalloid bolus RL 900 to 1000 mL
Lee 2009 Preoperative RL 5 mL/kg/hour RL 30 mL/kg/hour
Magner 2004 Preoperative RL 10 mL/kg RL 30 mL/kg
Maharaj 2005 Preoperative RL 2 mL/kg per hour fasted RL 3 mL/kg per house fasted
McCaul 2003 Intraoperative No crystalloid bolus RL 1.5 mL/kg per hour fasted
  Intraoperative   D5RL 1.5 mL/kg per hour fasted
Monti 1999 Preoperative No crystalloid bolus RL 1000 mL
Murshed 2012 Preoperative RL 1.5 mL/kg per hour fasted RL 15 mL/kg
Najafianaraki 2010 Preoperative RL 2 mL/kg per hour fasted RL 2 mL/kg per hour fasted then RL 10 mL/kg
Onyando 2014 Preoperative No crystalloid bolus RL "maintenance" rate per hour fasted (maximum 1000 mL)
Ooi 1992 Preoperative No crystalloid bolus 20 mL/kg 4% dextrose/0.18% saline solution
Paganelli 2008 Intraoperative NS 10 mL/kg/hour NS 1000 mL bolus then 10 mL/kg/hour
Sharma 2010 Preoperative RL 10 mL/kg RL 20 mL/kg
  Preoperative   RL 30 mL/kg
Shin 2007 Preoperative RL 2 mL/kg RL 20 mL/kg
Singh 2013 Preoperative No crystalloid bolus RL 30 mL/kg
Soleimani 2018 Preoperative NS 1.5 mL/kg/hour NS 1.5 mL/kg/hour then RL 5 mL/kg
  Intraoperative   NS 1.5 mL/kg/hour then RL 5 mL/kg
Spencer 1988 Intraoperative No crystalloid bolus RL 1000 mL
Yilmaz 2014 Intraoperative NS 10 mL/kg/hour NS 20 mL/kg/hour
Yogendran 1995 Preoperative Plasmalyte 2 mL/kg Plasmalyte 20 mL/kg
Yoon 2008 Intraoperative RL 2 mL/kg RL 18 mL/kg

D5RL: dextrose 5% in Ringer's Lactate; D5W: dextrose 5% in water, NS: normal saline, RL: Ringer's Lactate