Table 2.

Univariable and multiple Cox regression analyzing women diagnosed with cancer vs. non-cases*.

Factors	Univariable analysis		Multivariable regression analysis		n, cases
	HR (95% CI)	P-value	HR (95% CI)	P-value
BMI
Q1	(ref)	—	(ref)	—	1067, 181
Q2	0.95 (0.77–1.17)	0.63	0.90 (0.73–1.12)	0.34	1062, 176
Q3	0.99 (0.81–1.22)	0.95	0.91 (0.73–1.14)	0.42	1043, 179
Q4	0.97 (0.79–1.20)	0.81	0.88 (0.70–1.10)	0.26	1029, 177
Recreational walking
(<5 times/week)	(ref)	—	(ref)	—	1153, 210
(≥5 times/week)	0.87 (0.74–1.02)	0.09	0.89 (0.76–1.05)	0.18	3048, 503
Exercise habits
(<1 time/week)	(ref)	—	(ref)	—	1268, 229
(≥1 time/week)	0.89 (0.76–1.04)	0.15	0.93 (0.79–1.10)	0.40	2449, 484
Education
School (9 years)	(ref)	—	(ref)	—	3007, 517
High school (12 years)	0.95 (0.79–1.14)	0.57	0.94 (0.78–1.13)	0.51	899, 143
University (17 years)	1.01 (0.76–1.34)	0.97	0.96 (0.72–1.28)	0.77	295, 53
Smoking
Never	(ref)	—			1994, 294
Former	1.34 (1.13–1.59)	<0.001	1.29 (1.09–1.53)	0.003	1270, 246
Current	1.45 (1.20–1.76)	<0.001	1.39 (1.15–1.69)	<0.001	937, 173
Childbirth
(<1 child)	(ref)	—	(ref)	—	448, 88
(≥1 child)	0.87 (0.70–1.10)	0.25	0.87 (0.70–1.10)	0.24	3128, 625
Alcohol
(<7 units/week)	(ref)	—	(ref)	—	2815, 470
(≥7 units/week)	1.09 (0.93–1.28)	0.27	1.05 (0.89–1.23)	0.56	1386, 243
Central Obesity
Q1	(ref)	—	(ref)	—	1053, 151
Q2	1.10 (0.88–1.37)	0.40	1.14 (0.90–1.43)	0.27	1049, 167
Q3	1.21 (0.97–1.50)	0.09	1.26 (1.00–1.58)	0.05	1048, 183
Q4	1.45 (1.17–1.79)	<0.001	1.50 (1.20–1.88)	<0.001	1051, 212

*Women with no history of cancer.

Univariable and multivariable adjusted analysis was conducted on the complete dataset: n = 4201, cases = 713.

Abbreviations: BMI, Body Mass Index.