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. 2019 Mar 29;10:1439. doi: 10.1038/s41467-019-09497-z

Table 1.

Comparison of relevant methods for structuring fused silica glass

Method 3D capability 3D microvoidsa Resolution Surface quality Literature
Etching
Wet chemical etching ~1 µm ~1–10 nm (Ra) 37,38
Dry etching <1 µm 0.5 (rms)–2 nm (Ra) 39,40
Mechanical
Powder blasting >10 µm 0.1–10 µm (Ra) 41
Laser-assisted
Laser-assisted etching + + 1–2 µm 0.1–0.2 µm (rms) 42–44
Backside etching 2 µm 0.05–0.5 µm 45
Replication
Sol-gel <1 µm n.a. 3
Nanocomposites <1 µm 2 nm (rms) 21,23
Precision glass molding ~1 µm 2 nm 2,46
Additive
Stereolithography nanocomposites ++ 60 µm 2 nm (rms) 22
Sol-gel ++ 200 µm n.a. 47
Stop flow lithography 10 µm 6 nm (rms) 48

aSuitability to create microvoids with a size of 1–100 µm