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. 2019 Mar 29;9:5329. doi: 10.1038/s41598-019-41846-2

Table 3.

Baseline characteristics in cycles that did or did not result in pregnancy after treatment by antagonist protocol.

Pregnancy (482) No pregnancy (1519) p
Age (years)
≤28 y 149 (30.91%) 285 (18.76%) <0.001
≤35 y 210 (43.57%) 560 (36.87%)
≤37 y 56 (11.62%) 160 (10.53%)
≤39 y 42 (8.71%) 159 (10.47%)
≤41 y 19 (3.94%) 153 (10.07%)
≥42 y 6 (1.24%) 202 (13.3%)
The times of ART
1–2 456 (94.61%) 1349 (88.81%) <0.001
3-4 25 (5.19%) 145 (9.55%)
≥5 1 (0.21%) 25 (1.65%)
OSI <0.001
≤0.1 26 (5.39%) 194 (12.81%)
≤0.3 199 (41.29%) 698 (46.07%)
≤0.5 172 (35.68%) 302 (19.93%)
≤0.6 19 (3.94%) 66 (4.36%)
≤0.8 35 (7.26%) 67 (4.42%)
≤1 18 (3.73%) 62 (4.09%)
≤1.2 5 (1.04%) 36 (2.38%)
>1.2 8 (1.66%) 90 (5.94%)
Basal FSH 8.38 (2.49) 8.68 (3.47) 0.04
Number of oocytes retrieved 8.4 (4.16) 8.47 (6.95) 0.768
Number of MII oocytes 7.57 (3.83) 7.51 (5.88) 0.788
Number of embryos transferred 1.8 (0.48) 0.69 (0.90) <0.001
Duration of infertility (years) 3.81 (3.22) 4.57 (3.97) <0.001
Cause of female infertility
cause1 101 (20.95%) 358 (23.57%) 0.063
cause2 235 (48.76%) 641 (42.2%)
cause3 138 (28.63%) 479 (31.53%)
cause4 8 (1.66%) 41 (2.7%)
Estradiol on day of HCG (pg/ml) 2215 (1218.36) 2435.07 (2001.18) 0.004
Progesterone on day of HCG (ng/ml) 0.86 (0.30) 1.06 (0.60) <0.001
LH on day of HCG (mIU/ml) 3.25 (2.46) 3.73 (6.55) 0.017
Endometrial thickness (mm)
<7 8 (1.66%) 87 (5.85%) <0.001
7–10 160 (33.20%) 579 (38.96%)
>10 314 (65.15%) 820 (55.18%)
Antral follicle count 9.59 (6.96) 9.21 (7.52) 0.3
BMI (kg/m2) 21.9 (2.85) 22.22 (2.84) 0.035

Data are mean(SD) or number (percentage).

BMI: body mass index (kg/m2);

OSI: ovarian sensitivity index.

Cause1: ovulation factor.

Cause2: non-ovulation factor.

Cause3: ovulation factor plus non-ovulation factor.

Cause4: unexplained,etc.

Gn: gonadotropin.

aTwo-sample t-test.

bPearsonχ2 test.