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. 2019 Mar 29;9:5378. doi: 10.1038/s41598-019-41801-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Corresponding mt/gDNA ratio in embryo culture medium when the score of ICM is different. At D3, the mt/gDNA ratio corresponding to different score of ICM in the embryo culture medium (a). Mt/gDNA ratio corresponding to different score of ICM in D5 embryo culture medium (b). According to the scores of ICM in each blastocyst (A–C), the samples were divided into three groups, A, B, and C, such as the abscissa. The ordinate represents the ratio of mt/gDNA in the culture medium. One black dot, black triangle or black square represents one sample. Data are means ± SEM.