Table 3.

Z-Drug PRR Values

	PRR Zolpidem vs Zaleplon (PRR− and PRR+)	PRR Zopiclone vs Zaleplon (PRR− and PRR+)	PRR Zolpidem vs Zopiclone (PRR− and PRR+)
Misuse/abuse ADRs	0.57 (0.55–0.59)	0.48 (0.43–0.53)	1.16 (1.11–1.21)
Dependence ADRs	2.00 (0.82–4.8)	2.00 (0.81–4.80)	1.00
Withdrawal ADRs	0.79 (0.76–0.81)	0.56 (0.29–1.06)	1.38 (1.27–1.49)
Overdose ADRs	2.90 (2.31–3.60)	5.00 (4.00–6.2)	0.58 (0.56–0.60)

Abbreviations: ADR, adverse drug reaction; PRR, proportional reporting ratio.