Table 2.

Cytotoxicities of selected compounds (IC₅₀ μM)

Compounds	HL-60	PC-3	MDA-MB-231
1a	12.08 ± 0.84	> 50	> 50
1b	19.24 ± 1.51	> 50	18.46 ± 1.65
3	19.78 ± 2.09	> 50	> 50
4	18.00 ± 1.04	> 50	> 50
6	15.56 ± 0.51	> 50	> 50
9	> 50	> 50	> 50
10	10.43 ± 0.31	> 50	> 50
11	> 50	> 50	> 50
12	10.77 ± 0.13	> 50	> 50
19	2.62 ± 0.74	21.87 ± 1.94	7.94 ± 0.94
20	4.50 ± 0.17	11.77 ± 0.19	11.97 ± 0.65
21	3.07 ± 0.16	27.11 ± 1.49	13.30 ± 1.09
22	9.64 ± 0.34	20.60 ± 1.64	14.59 ± 1.26
23	1.00 ± 0.21	11.95 ± 1.36	9.40 ± 1.28
24	6.18 ± 0.31	14.99 ± 1.28	15.96 ± 0.46
25	4.47 ± 0.14	14.57 ± 1.27	11.55 ± 1.25
27	1.89 ± 0.54	22.94 ± 1.97	> 50
28	4.52 ± 0.97	20.72 ± 2.04	16.37 ± 1.32
5-FU a	2.20 ± 0.08	25.98 ± 1.08	38.69 ± 2.84

IC₅₀ values expressed as mean ± standard deviation, n = 3

^aPositive control