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Release of EVs and its contents. Primarily, the EVs are originally derived from lysosomes and late endosomes. Then, they can be released into the extracellular environment. The contents of EVs, which contain DNAs, mRNAs, small RNAs, and proteins can be transferred from the original cell to their target cells in local microenvironment or at distant site that can possibly give rise to intercellular communication networks. Abbreviations: EVs, extracellular vesicles
