Table 1.
Characteristics of the case participants and controlsd
| Characteristics | ICASO(n = 250) |
|---|---|
| Age(years) | |
| Mean ± SD [Range] | 57.8 ± 8.6 [28–70] |
| Female, n(%) | 77(30.8) |
| Risk factors, n(%) | |
| Smoking | 97(38.8) |
| Drinking | 63(25.2) |
| Hypertension | 152(60.8) |
| Diabetes | 60(24.0) |
| Hyperlipemia | 95(38.0) |
| Clinical symptoms, n(%) | |
| Hemorrhage | 7(2.8) |
| Infarction | 165(66.0) |
| Ischemia | 77(30.8) |
| Other | 9(3.6) |
| Multiple stenosis | 199(79.6) |
| Location | |
| Anterior circulationa | 36(14.4) |
| Posterior circulationb | 99(39.6) |
| Multiple circulationc | 111(44.4) |
| Others | 4(1.6) |
aAnterior circulation = ACA Anterior cerebral artery, MCA Middle cerebral artery, ICA Internal carotid artery
bPosterior circulation = BA Basilar artery, VA Vertebral artery, PCA Posterior cerebral artery
cMultiple circulation = including both Anterior and posterior circulation
dControl individuals were obtained from 1000 Genome Project Chinese Han Population and GeneSky in-house database, clinical characteristics were not available