Table 5.
Characteristics of RNF213 rare variants carriers and non-carriers
| Characteristics | Carrier(n = 39) | Non-carrier(n = 211) | p value |
|---|---|---|---|
| Age(years) | |||
| Mean ± SD | 60.5 ± 6.2 | 57.3 ± 8.9 | 0.028 |
| Female, n(%) | 12(30.8) | 65(30.8) | 0.996 |
| Risk factors, n(%) | |||
| Smoking | 16(41.0) | 81(38.4) | 0.756 |
| Drinking | 14(35.9) | 49(23.2) | 0.095 |
| Hypertension | 29(74.4) | 123(58.3) | 0.059 |
| Diabetes | 12(30.8) | 48(22.7) | 0.281 |
| Hyperlipemia | 14(35.9) | 81(38.4) | 0.768 |
| Clinical symptoms, n(%) | |||
| Hemorrhage | 3(7.7) | 4(1.9) | 0.137 |
| Infarction | 29(74.4) | 136(64.5) | 0.23 |
| Ischemia | 8(20.5) | 69(32.7) | 0.13 |
| Other | 1(2.6) | 8(3.8) | |
| Characteristics of cerebral artery stenosis, n(%) | |||
| Multiple stenosis | 29(74.4) | 170(80.6) | 0.377 |
| Location | |||
| Anterior circulationa | 4(10.3) | 32(15.2) | 0.688 |
| Posterior circulationb | 14(35.9) | 85(40.3) | |
| Multiple circulationc | 20(51.3) | 91(43.1) | |
| Others | 1(2.6) | 3(1.4) | |
aAnterior circulation = ACA Anterior cerebral artery, MCA Middle cerebral artery, ICA Internal carotid artery
bPosterior circulation =BA Basilar artery, VA Vertebral artery, PCA Posterior cerebral artery
cMultiple circulation = including both Anterior and posterior circulation