Table 1.
Demographic characteristics of participants in 4 COC studies combined in this analysis.
| Study | aWesthoff et al. | bEdelman et al. | cEdelman et al. | dNatavio et al. | Pooled |
|---|---|---|---|---|---|
| Number of Subjects | 28 | 19 | 32 | 10 | 89 |
| Age (years) | 25.5 ±4.5 | 29.5 ±5.1 | 29.0 ±4.7 | 35.2±3.9 | 28.7 ±5.4 |
| Weight (kg) | 77.5 ±19.4 | 83.2 ±25.7 | 106.6 ±17.7 | 71.8±9.6 | 88.5 ±23.8 |
| Height (cm) | 164.8 ±7.2 | 165.3 ±9.4 | 162.8 ±7.6 | 158.8±7.3 | 163.5 ±8.0 |
| Non-Hispanic | 20 (71.4) | 18 (94.7) | 30 (93.8) | 2(20) | 70 (79) |
| Normale | 13 (46.4) | 9 (47.4) | 0 (0) | 1(10) | 23 (26) |
| Overweighte | 0(0) | 0(0) | 0(0) | 6(60) | 6 (7) |
| Obesee | 15 (53.6) | 8 (42.1) | 23 (71.9) | 3(30) | 49 (55) |
| Extremely Obesee | 0 (0) | 2 (10.5) | 9 (28.1) | 0(0) | 11 (12) |
| BMI (kg/m2) | 28.4 (6.2) | 30.0 (9.1) | 39.4 (6.6) | 28.5(3.3) | 32.7 (8.4) |
| BSA (m2) | 1.84 (0.24) | 1.89 (0.25) | 2.09 (0.18) | 1.74(0.14) | 1.93 (0.25) |
a
Study from Westhoff et al.[13] administered LNG 150 mcg/EE 30 mcg.
b
Study from Edelman et al. [14] published in 2009 administered LNG 100 mcg/EE 20 mcg.
c
Another study from Edelman et al. [15] published in 2014 administered LNG 100 mcg/EE 20 mcg.
d
Study from Natavio et al. [16] administered LNG 150 mcg/EE 30 mcg.
e
Subjects with BMI 18.5–24.9 kg/m2 are considered normal, BMI 25.0–29.9 kg/m2 are overweight, BMI 30.0–39.9 kg/m2 are obese, and BMI greater than 40.0 kg/m2 are extremely obese.
All data are presented as n (%) or mean ± standard deviation.