Table 1:
CLE n = 226 |
SLE n = 165 |
ADM n = 136 |
AIBD n = 79 |
Control n = 84 |
|
---|---|---|---|---|---|
Demographics | |||||
Mean Age (s.d.) | 48.78 ± 14.60 | 40.17 ± 13.00 | 55.44 ± 12.95 | 65.09 ± 16.10 | 45 ± 13.96 |
Female Sex, n (%) | 166 (73%) | 152 (92%) | 123 (90%) | 44 (56%) | 33 (39%) |
Race, n (%) | |||||
White | 166 (73%) | 82 (50%) | 127 (93%) | 61 (77%) | |
Black | 50 (22%) | 68 (41%) | 4 (3%) | 9 (11%) | |
Asian | 7 (3%) | 8 (5%) | 4 (3%) | 8 (10%) | |
Other | 3 (1%) | 7 (4%) | 1 (1%) | 1 (1%) | |
Ethnicity, n (%) | |||||
Non-Hispanic | 218 (96%) | 156 (95%) | 129 (95%) | 79 (100%) | |
Hispanic | 7 (3%) | 9 (5%) | 3 (2%) | 0 (0%) | |
Unknown | 0 (0%) | 0 (0%) | 4 (3%) | 0 (0%) | |
Current smokers, n (%) | 79 (35%) | 34 (21%) | 8 (6%) | 4 (5%) | 13 (15%) |
Comorbidities, n (%) | |||||
HTN | 45 (20%) | 39 (24%) | 26 (21%) | 31 (39%) | 28 (33%) |
Diabetes | 6 (3%) | 9 (5%) | 5 (4%) | 11 (14%) | 1 (1%) |
Hypothyroid disease | 25 (11%) | 15 (9%) | 18 (14%) | 9 (11%) | |
Medications, n (%) | |||||
Hydroxychloroquine | 124 (55%) | 137 (83%) | 43 (32%) | 0 (0%) | 0 (0%) |
Chloroquine | 14 (6%) | 15 (9%) | 8 (6%) | 0 (0%) | 0 (0%) |
Quinacrine | 44 (19%) | 40 (24%) | 18 (13%) | 0 (0%) | 0 (0%) |
Methotrexate | 31 (14%) | 13 (8%) | 16 (12%) | 1 (1%) | 0 (0%) |
Azathioprine | 25 (11%) | 2 (1%) | 6 (4%) | 2 (3%) | 0 (0%) |
Thalidomide | 9 (4%) | 4 (2%) | 0 (0%) | 0 (0%) | 0 (0%) |
Mycophenolate Mofetil | 37 (16%) | 2 (1%) | 22 (16%) | 14 (18%) | 0 (0%) |
Prednisone | 86 (38%) | 21 (13%) | 42 (31%) | 32 (41%) | 0 (0%) |
Cyclosporine | 0 (0%) | 3 (1%) | 0 (0%) | 0 (0%) | 0 (0%) |
Rituximab | 2 (1%) | 0 (0%) | 1 (1%) | 21 (27%) | 0 (0%) |
Dapsone | 3 (1%) | 5 (3%) | 1 (1%) | 4 (5%) | 0 (0%) |
IVIG | 0 (0%) | 0 (0%) | 7 (5%) | 0 (0%) | 0 (0%) |
Mean SF-36 mental health score (s.d.) | 69.06 ± 20.53 | 62.90 ± 20.56 | 68.62 ± 20.86 | 73.47 ± 21.37 |
AIBD, autoimmune blistering diseases; ADM, amyopathic dermatomyositis; CLE, cutaneous lupus erythematosus; HTN, hypertension; SLE, systemic lupus erythematosus