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Particle sizes of spray-dried powder formulations.
| Formulations | Particle size (μm) | Water content (%) w/w | ||
|---|---|---|---|---|
| D10 | D50 | D90 | ||
| Meropenem-SD | 0.5 ± 0.1 | 1.1 ± 0.1 | 1.9 ± 0.2 | 8.8 ± 0.2 |
| Colistin-Meropenem | 0.9 ± 0.0 | 1.4± 0.1 | 2.2 ± 0.3 | 5.1 ± 0.2 |
| Meropenem-Rifampicin | 0.6 ± 0.1 | 0.9 ± 0.1 | 1.6 ± 0.3 | 4.4 ± 0.3 |
| Colistin-Meropenem-Rifampicin | 0.8 ± 0.1 | 1.2 ± 0.08 | 2.1 ± 0.2 | 3.0 ± 0.3 |
