Fig. 8.

EPC transplantation decreases vasculome/RECA1 ratio at day 7 post-stroke in the striatum peri-infarct area. a Quantitative analysis of fluorescent intensity revealed significant reduction of the inflammation-associated stroke vasculome BRM, IKB, Foxf1, and ITIH-5 and brain blood vessel (RECA1) ratio in the ipsilateral peri-infarct area of the striatum at 7 days post EPC transplantation (p’s < 0.01). b Photomicrographs correspond to the coronal sections of the ipsilateral hemisphere showing positive vasculome and brain blood vessel positive (RECA1) expression in the peri-infarct area of the striatum in stroke-vehicle and stroke-EPC treated animals. Arrows indicate co-localization of vasculome with RECA 1 staining for either BRM, IKB, Foxf1, and ITIH-5, Scale bar = 50 μm. Student t-test, p’s < 0.01. Data are expressed as mean ± SEM