Table 3.

Diagnostic criteria for invasive fungal sinusitis.

Adapted from deShazo et al. [10]

1. Mucosal thickening or air fluid levels compatible with sinusitis on radiologic imaging

2. Histopathologic evidence of hyphal forms within sinus mucosa, submucosa, blood vessels, or bone

3. To diagnose granulomatous invasive fungal sinusitis, histopathologic evidence of hyphal forms within sinus mucosa, submucosa, blood vessel or bone in association with granuloma containing giant cells is required. Concomitant stains for mycobacteria must be negative