Table 3.

Differences in variables between the two groups at baseline and after intervention and changes in variables from baseline

Variables	Ala54Ala carriers	Thr54 carriers	P-value
Fasting blood glucose
Baseline	9.0±2.9	8.5±2.4	0.160
After intervention	8.4±2.2	8.1±2.2	0.402
Change from baseline	–0.6±1.8	–0.3±1.5	0.263
TC
Baseline	4.91±1.13	4.79±1.06	0.099
After intervention	4.61±0.93	4.71±1.06	0.495
Change from baseline	–0.31±0.82	–0.08±0.75	0.057
Triglycerides
Baseline	2.17±1.87	1.80±1.29	0.001
After intervention	1.59±0.97	1.66±1.12	0.658
Change from baseline	–0.58±1.24	–0.14±1.08	0.015
HDL-c
Baseline	1.20±0.29	1.21±0.32	0.842
After intervention	1.18±0.26	1.21±0.32	0.463
Change from baseline	–0.03±0.18	0.00±0.16	0.358
LDL-c
Baseline	2.85±0.94	2.80±0.84	0.733
After intervention	2.74±0.80	2.82±0.81	0.496
Change from baseline	–0.11±0.65	0.02±0.57	0.163
HbA1c
Baseline	7.2±1.5	7.0±1.2	0.340
After intervention	6.9±1.0	6.9±1.4	0.670
Change from baseline	–0.4±1.5	0.1±1.4	0.218
GA
Baseline	18.4±4.8	17.9±4.3	0.438
After intervention	16.9±3.9	16.8±3.9	0.953
Change from baseline	–1.6±2.4	–1.1±1.8	0.116
IL-6
Baseline	2.82±2.73	2.64±3.08	0.680
After intervention	3.00±2.60	3.02±3.53	0.831
Change from baseline	0.18±2.19	0.38±1.35	0.416
TNF-α
Baseline	7.4±2.5	7.5±2.2	0.743
After intervention	10.0±8.4	9.5±4.5	0.658
Change from baseline	2.6±8.4	2.0±4.4	0.453

Notes: Data at baseline and after intervention are expressed as mean ± SD. Differences in variables between groups and changes from baseline were analyzed using the ANCOVA (generalized linear model) test with adjustments for sex, age, BMI, and course of disease.

Abbreviations: ANCOVA, analysis of covariance; BMI, body mass index; GA, glycated albumin; HbA1c, hemoglobin A1c; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; TNF-α, tumor necrosis factor alpha.