Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 26;12:2215–2224. doi: 10.2147/OTT.S200818

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Harat et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

The directions and frequencies of changes for each biomarker. The frequencies presented in arrows represent the percentage of changes measured within patients with a particular biomarker, while overall frequency is the percentage of alterations measured within whole group undergoing double surgery. Transformations into methylated MGMT, 1p/19q co-deletion, IDH1/IDH2 mutations, or MGMT methylation level altered two levels up were considered as change for a better molecular profile, while a profile was considered as transformation into a worse prognostic type when one of the above was no longer present or MGMT methylation decreased by least two categories.